발치와경화증에서 보이는 백악질성 골화
Cementoid Ossification in Socket Sclerosis
김연숙, 이보람, 곽윤영, 이석근,
소속 상세정보
김연숙 ( Kim Yeon-Sook ) - 청주대학교 보건과학대학 치위생학과
이보람 ( Lee Bo-Ram ) - 강릉원주대학교 치과대학 구강병리학교실
곽윤영 ( Kwak Yoon-Young ) - 강릉원주대학교 치과대학 구강병리학교실
이석근 ( Lee Suk-Keun ) - 강릉원주대학교 치과대학 구강병리학교실
KMID : 0829220120360010051
Abstract
Socket sclerosis can be an obstacle for orthodontic space closure, however, the precise histomorphogenetic mechanism has not been elucidated up to date. A 73 years old female complained of dull pain on palpation in the extraction site of the left maxillary first molar, and uncomfortable to use her complete denture. In panoramic X-ray view the socket sclerosis was clearly demarcated as a radiopaque outline of extracted root. In histological examination the socket sclerosis showed the basophilic deposition of cementum-like materials in the peripheral rim of trabecular bones instead of eosinophilic osteoid materials for intramembranous ossification. In the immunohistochemical staining for osteogenetic proteins, BMP-2 was strongly positive in the peripheral rim of trabecular bone, in which RANKL and osteoprotegerin were also consistently positive. Particularly, versican, a marker of cementum was also positive in the peripheral rim of the trabecular bone. Therefore, it is presumed that the trabecular bones of socket sclerosis were hypermineralized by cementoid ossification, producing cementum-like materials by osteoblasts/cementoblasts derived from the previous periodontium.
키워드
Immunohistochemistry; Periodontium-derived Osteoblasts/Cementoblasts
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